Preparation, Characterization and Manipulation of Conjugates between Gold Nanoparticles and DNA

نویسندگان

  • Gennady Eidelshtein
  • Moran Fattal
  • Gavriel Avishai
  • Benjamin Kempinski
  • Clelia Giannini
  • Alexander Kotlyar
چکیده

Here we described the preparation and characterization by atomic force microscopy of dumbbell-shaped conjugates between 450 bp double-stranded DNA polymer, poly(dG)-poly(dC), and 5 nm gold nanoparticles (GNPs). We have demonstrated that the size of the nanoparticles in the conjugates can be increased in a controlled fashion. Application of the conjugates for measuring the electrical conductivity of DNA is discussed.

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2016